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SkinPen Microneedling in Fresno
SkinPen Microneedling Treatments With PRP & Exosomes
SkinPen Microneedling is a minimally invasive skin rejuvenation procedure that stimulates your body’s natural healing response. Using a specialized SkinPen microneedling tool equipped with very thin needles, controlled micro-injuries are created on the skin’s surface. These micro-injuries trigger the production of collagen and elastin two essential proteins that support skin firmness, elasticity, and overall vibrancy.
At Pristine Ethereal Aesthetics in Fresno, we enhance traditional SkinPen microneedling treatments with Platelet-Rich Plasma (PRP) and topical Exosomes. These two powerful regenerative therapies elevate your results and promote more profound skin healing.
SkinPen Microneedling with PRP
What is PRP
Platelet-rich plasma (PRP) is a fluid that is extracted from components in your blood. A small sample is drawn and processed in a centrifuge to concentrate the platelets, which are packed with growth factors and skin proteins crucial for tissue repair and collagen regeneration.
How PRP Enhances SkinPen Microneedling
SkinPen Microneedling creates microchannels in the skin, allowing PRP to penetrate deeper into the tissue. This accelerates healing, reduces inflammation, and maximizes collagen production for optimal rejuvenation.
Benefits of PRP SkinPen Microneedling
- Reduces fine lines and wrinkles
- Improves skin texture and tone
- Aids in healing of acne scars, surgical scars, and stretch marks
- Lightens sunspots and hyperpigmentation
- Reduces pore size
- Promotes overall skin rejuvenation
SkinPen Microneedling with Exosomes
What are Exosomes?
Exosomes are powerful “cargo packets” naturally released by cells. They contain proteins, enzymes, RNA, and growth factors that support cellular repair, communication, and regeneration. In aesthetics, exosomes are applied topically after SkinPen microneedling to deliver their regenerative benefits directly into the freshly created microchannels.
Types of Exosomes Used
- Mesenchymal Stem Cell (MSC) Exosomes (Kimera): Derived from healthy placental tissue, rich in connective tissue–stimulating proteins.
- Bone-Marrow Derived Exosomes: Contain hematopoietic stem cell material, but with less connective tissue regeneration potential.
- Adipose Tissue Exosomes: Derived from fat cells, typically with lower regenerative potency.
- Umbilical Cord/Wharton’s Jelly Products: Contain low viability after freezing, limiting their effect.
At Pristine Ethereal Aesthetics, we use premium Kimera exosomes—single-donor, placental-derived, and optimized for skin repair and rejuvenation.
Packages
Kimera Exosome Packages
Full Face
$550 each | $1500 for 3 sessions
Full Face + Neck
$650 each or $1800 for 3 sessions
Nucleoskin (Synthetic Exosomes) Packages
Full Face
$450 each | $1200 for 3 sessions
Full Face + Neck
$600 each or $1500 for 3 sessions
Nucleoskin combines polynucleotides with hyaluronic acid, providing a bio-restructuring, plumping, and lifting effect for smooth, radiant skin.
Exosome Add-On with Tixel Treatments
Exosomes can also be used in conjunction with Tixel resurfacing treatments. Applying exosomes immediately before or after Tixel ensures faster healing, deeper absorption of growth factors, and enhanced skin regeneration.
Benefits of SkinPen Microneedling with PRP or Exosomes
- Stimulates natural collagen and elastin production
- Reduces fine lines, wrinkles, and scarring
- Improves texture, tone, and firmness
- Minimizes pores and pigmentation
- Enhances overall radiance and youthfulness
- Accelerates healing when combined with PRP or Exosomes
- Customizable to your skin type and goals
Frequently Asked Questions
What conditions can SkinPen Microneedling treat?
SkinPen Microneedling is highly effective for lessening the prominence of wrinkles, acne scars, surgical scars, sun damage, stretch marks, enlarged pores, and uneven skin tone.
What is the difference between SkinPen Microneedling with PRP and Exosomes?
PRP uses your body’s platelet-rich plasma to accelerate healing and collagen production. Exosomes, on the other hand, provide a concentrated dose of regenerative proteins and RNA that deliver additional repair and anti-aging benefits. Many patients choose based on their skin goals and budget, while others combine both for optimal results.
How many SkinPen Microneedling treatments will I need?
Most patients benefit from a series of 3–6 treatments spaced 4–6 weeks apart. There are a few options to choose from, depending on the condition of your skin, your goals, and the package of services you choose.
Is SkinPen Microneedling painful?
The treatment is well-tolerated. Prior to surgery, numbing cream is applied to minimize discomfort, and patients typically describe their feeling as mild pressure or tingling.
What is the downtime after a SkinPen Microneedling treatment?
Downtime is minimal. You may experience redness, mild swelling, or sensitivity for 24–72 hours, similar to a sunburn. With PRP or Exosomes, healing is faster and side effects are reduced.
When will I see the results of SkinPen Microneedling?
Initial improvements in skin tone and texture are often noticeable within a week. Collagen remodeling continues for several months, with optimal results visible at 2–3 months after completing a series of treatments.