Microneedling in Fresno
Microneedling
Microneedling is a minimally invasive skin rejuvenation procedure that stimulates your body’s natural healing response. Using a specialized microneedling tool equipped with very thin needles, controlled micro-injuries are created on the skin’s surface. These micro-injuries trigger the production of collagen and elastin—two essential proteins that support skin firmness, elasticity, and overall vibrancy.
At Pristine Ethereal Aesthetics in Fresno, we enhance traditional microneedling treatments with Platelet-Rich Plasma (PRP) and topical Exosomes. These two powerful regenerative therapies elevate your results and promote more profound skin healing.
Microneedling with PRP
What is PRP
Platelet-rich plasma (PRP) is a fluid that is extracted from components in your blood. A small sample is drawn and processed in a centrifuge to concentrate the platelets, which are packed with growth factors and skin proteins crucial for tissue repair and collagen regeneration.
How PRP Enhances Microneedling
Microneedling creates microchannels in the skin, allowing PRP to penetrate deeper into the tissue. This accelerates healing, reduces inflammation, and maximizes collagen production for optimal rejuvenation.
Benefits of PRP Microneedling
- Reduces fine lines and wrinkles
- Improves skin texture and tone
- Aids in healing of acne scars, surgical scars, and stretch marks
- Lightens sunspots and hyperpigmentation
- Reduces pore size
- Promotes overall skin rejuvenation
Microneedling with Exosomes
What are Exosomes?
Exosomes are powerful “cargo packets” naturally released by cells. They contain proteins, enzymes, RNA, and growth factors that support cellular repair, communication, and regeneration. In aesthetics, exosomes are applied topically after microneedling to deliver their regenerative benefits directly into the freshly created microchannels.
Types of Exosomes Used
- Mesenchymal Stem Cell (MSC) Exosomes (Kimera): Derived from healthy placental tissue, rich in connective tissue–stimulating proteins.
- Bone-Marrow Derived Exosomes: Contain hematopoietic stem cell material, but with less connective tissue regeneration potential.
- Adipose Tissue Exosomes: Derived from fat cells, typically with lower regenerative potency.
- Umbilical Cord/Wharton’s Jelly Products: Contain low viability after freezing, limiting their effect.
At Pristine Ethereal Aesthetics, we use premium Kimera exosomes—single-donor, placental-derived, and optimized for skin repair and rejuvenation.
Packages
Kimera Exosome Packages
Full Face
$550 each | $1500 for 3 sessions
Full Face + Neck
$650 each or $1800 for 3 sessions
Nucleoskin (Synthetic Exosomes) Packages
Full Face
$450 each | $1200 for 3 sessions
Full Face + Neck
$600 each or $1500 for 3 sessions
Nucleoskin combines polynucleotides with hyaluronic acid, providing a bio-restructuring, plumping, and lifting effect for smooth, radiant skin.
Exosome Add-On with Tixel Treatments
Exosomes can also be used in conjunction with Tixel resurfacing treatments. Applying exosomes immediately before or after Tixel ensures faster healing, deeper absorption of growth factors, and enhanced skin regeneration.
Benefits of Microneedling with PRP or Exosomes
- Stimulates natural collagen and elastin production
- Reduces fine lines, wrinkles, and scarring
- Improves texture, tone, and firmness
- Minimizes pores and pigmentation
- Enhances overall radiance and youthfulness
- Accelerates healing when combined with PRP or Exosomes
- Customizable to your skin type and goals
Frequently Asked Questions
Downtime is minimal. You may experience redness, mild swelling, or sensitivity for 24–72 hours, similar to a sunburn. With PRP or Exosomes, healing is faster and side effects are reduced.